This is more involved than just picking one for me. I converted to using Firefox exclusively years ago. And this had been a perfect solution for me up until last year.
Firefox has a couple of plug-ins that I just can’t live without. Firebug and IE Tab. Many times I will use Firebug to dig into other websites to see how they are building their pages or what technology it is based on. IE tab is a great way to verify cross browser compatibility when developing a site. I have found if I just build my UI in Firefox it is usually only a few steps away in IE, however the reverse is almost never true. IE tab also allows me to run my Windows Home Server (WHS) in several tabs. This results in running multiple Remote Desktop Sessions (RDP) some physical some virtual.